Dager W. Anticoagulation Therapy. A Clinical Practice Guide 2ed 2018
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Dager W. Anticoagulation Therapy. A Clinical Practice Guide 2ed 2018
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Although highly effective in preventing thromboembolic events, the safe management of anticoagulant therapy continues to be a major challenge, requiring constant monitoring and coordinated models of patient-centered care.
Anticoagulation Therapy: A Clinical Practice Guide, Second Edition, helps take the guesswork out of managing these therapies and provides essential recommendations.
New in This Edition:
- Extensive new information on direct oral anticoagulants (DOACs)
- Expanded information on anticoagulant reversal and expanded use of prothrombin complex concentrates
- New chapters on the use of anticoagulants in special patient populations, the use of anticoagulants in patients with mechanical devices, anticoagulation care delivery standards, regulatory issues, and more
- Four new appendices on the effect of DOACs on chemotherapy, nutritional influences, types of central nervous system hemorrhage, and use of anticoagulation in patients with coagulopathies
Dedication
Contributing Editors
Contributors
Preface
Acknowledgments
Abbreviations
Anticoagulation Medication Management
Introduction to Anticoagulation Management
Warfarin
Unfractionated Heparin
Low Molecular Weight Heparin and Fondaparinux
Parenteral Direct Thrombin Inhibitors
Thrombolytic Considerations When Used with Anticoagulants
Direct Oral Anticoagulants
Anticoagulation Reversal: Part I—Pharmacology of Agents Used for Reversal
Anticoagulation Reversal: Part II—Clinical Application
Transitions in Care—Periprocedural Bridging and Transitions Between Agents
Considerations in Special Populations
Conditions Requiring Anticoagulation Therapy
Venous Thromboembolism Prevention
Venous Thromboembolism Treatment
Atrial Fibrillation
Acute Coronary Syndromes
Prosthetic Heart Valves
Mechanical Circulatory Support Devices
Heparin-Induced Thrombocytopenia
Pregnancy
Pediatrics
Practical Measuring, Monitoring, and Coagulation Laboratory
Insights
Coagulation Laboratory Considerations
Thrombophilias
Essentials for Practice Success
Models and Standards of Anticoagulation Care Delivery
Regulatory and Practice Resources
Appendixes
Coagulation Cascade
Agents Implicated in Drug-Induced Thromboembolic Diseases
Nutrition Influence on Anticoagulation
Anticoagulants in Management of Ischemic Stroke or Transient Ischemic Attacks
Citrate Anticoagulation
Examples of Available Bleeding Definitions
Types of CNS Hemorrhage
Disseminated Intravascular Coagulation
Nondrug Causes of Thrombocytopenia
Drug-Related Causes of Thrombocytopenia
Examples of Transfusion-Related Reactions
Considerations for Transitioning from aPTT to Anti-Xa to Manage Heparin Therapy
PIONEER AF-PCI
Betrixaban APEX Trial
Index