Doyle M. Heterocycles from Carbenes and Nitrenes. Methods, Reactions...App 2023

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This book provides researchers in the fields of organic chemistry, organometallic chemistry and homogeneous catalysis with an overview of recent developments in the applications of reactions involving carbene and nitrene intermediates directed to the synthesis of heterocyclic compounds. Multiple pathways through which diverse heterocyclic compounds are accessed occur from a variety of carbene and nitrene precursors through C-H/X-H insertions, cycloadditions, ylide transformations, rearrangements, and cascade reactions. Catalytic processes that form metallo-carbenes and nitrenes offer unparalleled chemo-, regio-, and stereo-selectivities. Insights are provided into the scope of these methodologies and the inherent control of catalyst ligands on reaction selectivities.
Photo-Induced Carbene Transformations to Heterocycles
Heterocycles from Onium Ylides
Heterocycles from Sulfur Ylides
Heterocycles from Cascade Reactions via Carbene gem-Difunctionalization
Heterocycles from Cyclopropanation of Five-Membered Heteroarenes
Heterocycles from Cycloaddition Reactions
Alkynes as Carbene Precursors for the Synthesis of Heterocycles
Heterocycles from Donor and Donor/Donor Carbenes
An Overview of N-Heterocycle Syntheses Involving Nitrene Transfer Reactions